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View study Heffernan MA et al., "Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment," International Journal of Obesity, 2001

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At the 4-h time point, serum levels of alanine transaminase and aspartate transaminase (AST) were markedly higher in the hepsin / mice, indicating more severe liver damage compared with their wild-type counterparts (Fig