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And if someone's taking methylene blue for a specific health concern, like brain fog or fatigue, a primary care provider can also help address those issues, says Sharfstein
Knowing about them before they happen to you is the best defense
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A randomized, double-blind, placebo-controlled trial in 153 older adults taking the antidepressant citalopram found daily supplementation with 500 g vitamin B 12 , 2 mg of folic acid, and 25 mg of vitamin B6 for one year did not reduce the severity of depressive symptoms but increased the response to drug treatment and helped to prevent symptom relapse (112), suggesting B-vitamin supplementation might provide some benefit as an adjunct therapy
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