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Although, therapeutic (as opposed to prophylactic) relevance has yet to been assessed, our discovery highlights the potential of BHB and a ketogenic diet as a broadly applicable treatment to enhance functional T cell responses in nutrient-deprived environments, which are commonly observed in the context of infections but also tumour growth

B12 is naturally found in animal products such as meat, dairy, and eggs, which can make it challenging for vegetarians and vegans to obtain sufficient amounts through diet alone

Our analysis demonstrates that thiamine insufficiency restricted to the gastrointestinal system, i.e., lacking well-known symptoms of dry and wet beriberi, may arise through (i) a disbalance between the nutrient influx and efflux in the gastrointestinal system due to increased demands of thiamine by the organism

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