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As a consequence, the peptide might lead to fat accumulation rather than reduction, as its substantial hunger-inducing impact could offset the fat-burning benefits of increased GH levels
It has been rigorously tested for this use and is considered safe for most adults when managed by a physician
doi: 10.1007/s00520-003-0443-y 135 HuMYuanLZhuJ
SELECT trial: 20% reduction in MACE (HR 0.80, 95% CI 0.72-0.90)
Metformin users, common among type 2 diabetes patients who then add semaglutide, face a double hit since metformin independently reduces B12 absorption by 10-30% over long-term use
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