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Yes, acid exposure and lower saliva can wear enamel and expose nerve endings, making teeth more sensitive
SdaA was reported to be the gene encoding either the structural gene of L-SD that catalyzes the deamination of serine to pyruvate or a positive activator of transcription [31]
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doi:10.1056/NEJMoa2032183 Jastreboff AM, Aronne LJ, Ahmad NN, et al