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Headaches: Headaches can occur as a side effect, though they are generally mild and short-lived

MIC B12 injections as monotherapy produce minimal weight loss (1-2 pounds over 12 weeks, not statistically significant)

Whether reducing NNMT activity would directly reverse these changes in humans remains an open research question

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Energy recovery typically occurs within 2 to 4 weeks of starting supplementation, allowing patients to engage in regular exercise and maintain adherence to their treatment plan