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Diabetes 69 , 25892602 (2020)
This dual mechanism is what distinguishes tirzepatide from single-receptor GLP-1 medications like semaglutide
Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus
Tirzepatide mimics this hormone but lasts an entire week, creating sustained appetite suppression and blood sugar control that natural GLP-1 could never achieve
For some, they can also offer much-needed validation after years of being told they simply werent trying hard enough
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