doi:10.1038/s41398-020-0694-0 Blake MJ, Trinder JA, Allen NB
These include regulating cell signaling, enzyme function, gene expression, and cell differentiation and proliferation
doi: 10.1016/j.ydbio.2017.05.012
The most dangerous carcinogens in tar are the polycyclic aromatic hydrocarbons such as nitrosamine ketones derived from nicotine and benzopyrenes, organic compound butadiene and redox carcinogenic metal chromium, non-redox cadmium, and arsenic, and radioactive polonium (Sun et al
Among these compounds, nordihydroguaiaretic acid showed no significant effects in two phase-II clinical trials for the treatment of prostate cancer and CNS tumors