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Human clinical trials in androgenetic alopecia patients have reported modest improvements in hair density (10-20% increases) and hair shaft diameter (5-15% increases) following 6-12 months of daily topical GHK-Cu application, though results generally remain inferior to established treatments including minoxidil or finasteride

These modifications reduce binding to IGF binding proteins substantially, extending the half-life while maintaining receptor activation

Resources: Collins L, Costello RA

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