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Species differences in metabolism, receptor expression, and pharmacokinetics mean that effective doses in rats do not predict safe or effective doses in humans

References Pollard, B., & Pomfrett, C

It is preferably taken after a meal with the consistency of the recommended dosage

Glavas, Iphigenia Kanara, Krishna Kodukula, Julie Pernokas, Mark Pernokas, Carl A

"While glutathione is a powerful antioxidant and theoretically could reduce oxidative stress in melanocytes, there is no robust clinical data showing that increasing dietary or supplemental glutathione can reliably prevent or reverse gray hair in humans." The body's regulation of hair pigmentation is complex, he added, and once melanocytes lose their ability to produce pigment, antioxidants alone are unlikely to restore it