natural glp-1 receptor Central glucagon-like peptide 1 activation inhibits Toll-like receptor agonist-induced inflammation Dual-Target Insight into Drug Discovery

GLP-1 is an incretin hormone that stimulates insulin secretion, suppresses glucagon, and promotes satiety

All study participants were randomly assigned to an experimental treatment group that received subcutaneous injection of cagrilintide, once-weekly, in doses of either 0.3, 0.6, 1.2, 2.4, or 4.5 mg, as well as a one-daily 3.0 mg dose of liraglutide, and a volume matched placebo for control purposes

Beta-sitosterol: This plant compound is taken as a supplement to treat conditions such as benign prostate hyperplasia

Accessed at www.nejm.org/doi/full/10.1056/NEJMoa2206038

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