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User experimentation suggests that longer initial treatment periods (6+ months continuous) support better benefit retention during subsequent breaks, complete discontinuation breaks of 1-2 months show acceptable benefit maintenance for most users, and very extended breaks (3-6+ months) increase risk of regression toward pre-treatment baseline particularly for short initial treatment courses

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For semaglutide specifically, the SmPC advises discontinuation at least 2 months before a planned pregnancy due to its long half-life

And again, as Steph can attest thanks to that class in pharmacy school, no matter what kind of beverage its mixed with and even if its covered with a lid, that awful smell still travels right up to the nose