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This reduction in T3 can manifest as hypothyroid symptoms such as fatigue, weight gain, and cold intolerance, even though T4 levels may appear normal
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With semaglutide, weight loss tends to slow significantly after 20-30 weeks, approaching a plateau by week 40-50
If you notice any of these, it could indicate a problem with contamination or degradation
Otherwise, standard annual thyroid function monitoring is appropriate for stable patients
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