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Eaton S, Fukumoto K, Stefanutti G, Spitz L, Zammit VA, Pierro A: Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis

This is the first time the active substance is metabolised in the liver, referred to as the first pass metabolism

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Oral supplements are more expensive than topical skincare products