melatonin glutathione SandMan™ Bullet (Glutathione & Melatonin)+ The role of melatonin, glutathione

Warsy A, Mohsen A

Glutathione activates the Nrf2/HO-1 signaling pathway, a critical transcriptional regulator of antioxidant gene expression

Intravenous Glutathione IV glutathione carries additional risks beyond oral supplementation [60]: Skin rashes Abdominal pain Thyroid dysfunction Liver dysfunction Kidney dysfunction and possible kidney failure Stevens-Johnson syndrome (rare) These risks have been documented particularly in the context of IV glutathione used for cosmetic skin lightening, where it may be administered repeatedly at high doses (600-2,400 mg per session) [60]

Heres a breakdown by category: Fruits Berries (Rich in anthocyanins and vitamin C): Blueberries Strawberries Raspberries Blackberries Citrus Fruits & miscellaneous Oranges Grapefruits Lemons Pomegranate Apples Grapes (especially dark varieties) Vegetables Kale Spinach Broccoli Brussels sprouts Carrots Sweet potatoes Red bell peppers Nuts and Seeds Almonds Walnuts Sunflower seeds Flaxseeds Chia seeds Legumes and Whole Grains Lentils Black beans Kidney beans Quinoa Oats Herbs and Spices Turmeric (Curcumin) Ginger Cinnamon Garlic Beverages- Green tea (Catechins) Black tea Coffee Red wine (in moderation) A Summary | Davins viewpoint on supplements for melasma & pigmentation Dr Davin Lim | Dermatologist The Melasma Clinic, Brisbane | Sydney Supplementation with antioxidants is a novel but not primary approach in managing melasma

Meanwhile, genistein increased the levels of Nrf2, which is vital to the GSH system [132,133,134]