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Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs
The NHS notes that adults need only around 1.5 micrograms a day, which a normal mixed diet covers with ease
These models help researchers explore how localized biological systems maintain communication and regulatory balance under experimental conditions