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Yes, tirzepatide can be stopped suddenly without a formal tapering schedule, as there is no evidence of withdrawal syndrome

GLP-1R agonists show great potential in AD, but key challenges, such as blood brain barrier (BBB) penetration, clinical trial inconsistency, long-term safety and precision therapy, need to be addressed

Abstract Background: Glucagon-like peptide-1 (GLP-1) receptor agonists, including tirzepatide, are increasingly prescribed for obesity and type 2 diabetes mellitus

When paired with insulin or sulfonylureas, hypoglycemia risk rises, so prescribers often lower those doses

if Yes, end date should be blank or treated as ongoing, and at least one outcome (intolerance or inadequate response) should be captured where applicable