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doi: 10.1038/nn.4540, 150 van BloemendaalL.RgI

Room temperature storage accelerates degradation over weeks to months

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In microglia, GLP-1R activation via PI3K/Akt signaling also reduces neuroinflammation by modulating NF-B activity, decreases the production of pro-inflammatory cytokines, increases anti-inflammatory markers such as IL-10, IL-4, Arginase, and CD206, and the transformation of microglia into an anti-inflammatory state