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The most common issues include nausea, vomiting, diarrhea, abdominal pain, and constipation, though more serious side effects such as pancreatitis, gastroparesis, and bowel obstruction have been reported

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In addition to a local effect, dietary Gln supplementation has been described to cause an increase of the systemic Gln concentration, which may also sustain the health and function of immune and epithelial cells 39

Cumulative kidney complication risk by 50 years of type 1 diabetes: the effects of sex, age, and calendar year at onset