Natural killer cytotoxicity increased twofold in the high-dose group versus placebo at 3 months
Oral semaglutide was superior to placebo, sitagliptin, and liraglutide and similar to empagliflozin, with losses up to 4.44 kg compared with 0.53.6 kg for active-comparator arms and 0.41.4 kg compared with placebo [35,36,37,38,39,40]
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Al-Aly emphasized that his study also highlighted potential downsides to the medications, including an increased risk of gastrointestinal problems such as nausea, vomiting, diarrhea, and in rare cases paralysis of the stomach
It can happen (over time) if you consume more calories than your body needs to run optimally