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This weight loss itself is highly beneficial for managing PCOS, as losing even 5-10% of body weight can improve insulin sensitivity, potentially regulate menstrual cycles, reduce androgen levels, and improve fertility in some women

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MT-1 (Melanotan I) acts as a non-selective melanocortin receptor agonist and stimulates pigmentation primarily through MC1R activation in melanocytes, which regulates melanin synthesis and increases eumelanin production

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