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Alcohol- and other substance-use disorders may well benefit from the effects of GLP-1RAs on dopamine and opioid pathways that are dysregulated in addiction 243 , as seen in some of the studies we identified, and the same could also apply to other under-investigated disorders with similar underlying dysfunctions (for example, gambling disorder)
Non-binary, transmasculine and/or other gender variant people might feel comfortable maintaining a microdose, or a lower dose of testosterone, for more gradual changes
Fat Loss Growth hormone stimulates lipolysis , particularly visceral fat burning
Compared with placebo, GLP-1RAs treatment in T2DM patients significantly reduced the risk of death from cardiovascular disease and fatal/non-fatal stroke in cardiovascular outcome trials (Qin and Song, 2022)
Legality of Marketing and Selling for Human Use As mentioned above, setting aside food and food supplements, it is not legal to sell drugs or compounds for human consumption without MHRA approval
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