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Some Hashimoto's patients, particularly those with significantly compromised thyroid function, persistent untreated insulin resistance, or cortisol dysregulation, may experience less dramatic results

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The onset of reactions varied, occurring between 4 weeks and 3 years after medication initiation

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Distribute across 34 eating occasions at ~0.30.4 g/kg per meal to reach the leucine threshold that maximizes muscle protein synthesis, approximately 2.53.0 g leucine per meal for most adults and toward the upper end in older adults