Benoist 2014, PMID 25187433, retracted 2025 per notice PMID 40312093) is potentiation of hepatocyte growth factor (HGF) signaling at the c-Met (MET) receptor, driving dendritic spine formation and synaptogenesis via PI3K-AKT
Most compounds tend to have one or two main functions, while GHK-Cu appears to influence several biological processes
The mechanism underlying these rejuvenating effects involves selective clearance of senescent cells expressing high levels of SASP factors
Gut health: Support microbiome diversity through probioticrich foods and adequate fiber intake, particularly relevant for inflammatory bowel conditions
Anti-anxiety effects In an earlier experiment, from 2015, rats injected with 0.5mcg/kg of GHK were able to spend more time exploring a maze and less time in an immobile freeze reaction, suggesting that the peptide reduced their fear and anxiety.27 Wound healing As with the topical route of administration, an injection of GHK-Cu may be able to enhance your bodys wound-healing process