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Freezing causes ice crystal formation that physically disrupts peptide chains
Enhanced endothelial cell proliferation, migration, and tube formation were observed in laboratory studies accompanying the animal experiments
This includes patients with acute muscle strains, tendon irritation, ligament sprains, plantar fascia irritation, Achilles tendinopathy, patellar tendinopathy, rotator cuff irritation, tennis elbow, golfers elbow, or localized joint-adjacent soft-tissue pain
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