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showed that treatment of AR rats with baicalin reduced IgE, histamine, IL-4, IL-13, IL-6, and TNF- levels in serum and also reduced nasal sneezes in behavioral tests ( 3.2.3 Cirsilineol Cirsilineol (4,5-Dihydroxy-3,6,7-trimethoxyflavone) is a bioactive flavone with anti-inflammatory and anti-allergic properties that can protect against OVA-induced AR, according to a study in mice
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