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Like all medications, these can have side effects
There is a best fit for a given patient and goal
While tirzepatide does increase metabolism through its own mechanisms, dramatic or unexpected weight loss should prompt a thyroid function check
Native IGF-1 has a frustrating pharmacokinetic limitation: it binds tightly to a family of IGF binding proteins (IGFBPs, particularly IGFBP-3) that sequester it in circulation and keep its free half-life to roughly 15-20 minutes
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Without intervention, most patients return to near their pre-treatment weight within approximately 18 months
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