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This extrarenal production allows tissues to generate active vitamin D independently of systemic hormone levels, explaining why adequate 25(OH)D concentrations are necessary even when circulating 1,25(OH)2D levels appear normal
Cellular dynamics of myogenic cell migration: molecular mechanisms and implications for skeletal muscle cell therapies
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Theoretical risks of sustained angiogenic stimulation (promoting vascular supply to undetected pathological tissue) grow proportionally with the duration of use, as cumulative VEGF upregulation exceeds the controlled, injury-localized window intended by short-cycle research protocols
Biodistribution and therapeutic effects in orthotopic osteosarcoma mouse model Based on these promising findings, the biosafety of Ru(II)-OH, NP2, or NP4 at a doses of 2 mg Ru/kg was studied upon intravenous injection into the tail vein of healthy female mice on the days 1, 4, and 7
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