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Furthermore, A-RDN enhanced GLP-1-induced diuresis and natriuresis as well as T-RDN, suggesting that afferent renal nerve is essential for regulating the response of increase in RSNA to GLP-1 described above

Related expressional change of Hif-1alpha to the neuroprotective activity of exendin-4 in transient global ischemia

doi: 10.1002/ctm2.1184 576 KrugerKMyeonghyunYvan der WielenNKokDEHooiveldGJKeshtkarSet al

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In aging terms, this is a direct intervention on altered intercellular communication, easing the chronic inflammatory signaling that drives fibrosis