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In females, L2-Cmu mAb treatment led to a slight, albeit significant reduction in red blood cells (RBCs), hemoglobin (Hb), hematocrit (Hct), white blood cells (WBCs), lymphocytes (Supplementary Table 2), and serum phosphorus (Supplementary Table 3), though most values, with the exception of WBCs, remained within the normal range, and were less severely affected than previously reported with Ganitumab in young CD1 mice 26

The addition of 1.5 mM GSH resulted in a total of 81 vitrified oocytes, with 58 oocytes surviving (72.28.6)%, 7 with zona pellucida fractures (4.91.1)%, 7 with cytoplasmic shrinkage (12.33.8)%, and 7 with cytoplasmic lysis (10.63.7)% (Table 4)

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Omarigliptin is a long-acting DPP-4 inhibitor for once weekly dosing that is presently approved in Japan, but not in Europe or American countries (20)