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Toxicity predictions performed using the admetSAR 2.0 server (Table 5) indicated that six of the eight top compoundstriptocalline A, regeol A, 3,5-diprenylgenistein, bassic acid, 6,8-diprenylgenistein, and trans-dehydrocrotoninwere non-carcinogenic and non-mutagenic, with acute oral toxicity classified as Level III (moderate toxicity)
behavior change in terms of diet and exercise is needed for the drug to be effective