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This ordinarily creates no problem, except perhaps in rare cases of eye nerve damage, where the body is only marginally able to use this form due to high cyanide levels in the blood due to cigarette smoking, and thus requires cessation of smoking, or else B12 given in another form, for the optic symptoms to abate
Trenkwalder, C
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However, this IF-mediated pathway is saturable, with absorption plateauing at about 1.52 micrograms per dose
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