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GLP-1s, however, may also exert direct hormonal effects as GLP-1 receptors can be found across the hypothalamus-pituitary-ovarian (HPO) axis and influence gonadotropin release and follicle development

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10.1038/tp.2012.61 22

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The trial aims to enroll 700 participants, and will run 78 weeks (estimated readout 1H 2025)

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1 Introduction Central nervous system (CNS) injuries, including neurodegenerative diseases and stroke, pose a significant global health burden as the leading cause of disability and the second most common cause of death globally (Chin and Vora, 2014)

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