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Another strategy involves the use of PARP inhibitor BGP-15, which might protect against CC, to enhance mitochondrial homeostasis 260,261
The FDA approved it in 2012 for chronic weight management in adults with a BMI of 30 or greater, or a BMI of 27 or greater with at least one weight-related comorbidity such as high blood pressure, type 2 diabetes, or high cholesterol
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If gonadectomy is recommended, the possibility of cryoconservation, if vital sperms are found, should be discussed with the patient [174, 175]
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