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Gut barrier dysfunction and gut swelling can affect brain function through multiple mechanisms including passage of swelling mediators across the blood-brain barrier, start of the vagus nerve by gut signals, and alterations in neurotransmitter production by gut bacteria
The former finding may be associated with proliferation of neoplastic cells through activation of the signaling pathway via fibroblast growth factor 2 (FGF2) and stromal cell-derived growth factor-1 (SDF1)
Journal of Aging Science, 4 (3), 1000166
How GLP-1s Affect Appetite When You Have Type 2 Diabetes GLP-1 medications work similarly in people who are taking them for type 2 diabetes as they do in people taking them for weight loss, although the research is still ongoing, says Jennifer Nasser, PhD, RD, an associate professor of nutrition sciences at Drexel University in Philadelphia and spokesperson for the Obesity Society
