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TGF- inhibition prevents pathological remodeling of cardiac tissue, reduces fibrosis, and maintains post-injury cardiac function ( 3.2.5 Interaction with cardioprotective signal pathways Flavonoids can also affect various signaling pathways that are important for the regulation of cardiovascular function
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3d), as did treatment with other TS-targeted antifolates pemetrexed and methotrexate in colon (Extended Data Fig
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Since there is evidence to prove that these result can relate to humans, these results can be used to hypothesize the involvement of Zearalenone in developing liver, kidney and other types of cancer in humans
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