It has been suggested that keratinocytes, through the release of biological mediators, proopiomelanocortin (POMC)-derived peptides, basic fibroblast growth factor, and endothelins, regulate proliferation and differentiation of melanocytes and stimulate melanogenesis through receptor-mediated signalling pathways [20]
This keeps the calculation from becoming detached from the label that produced it
Colhoun HM, Lingvay I, Brown PM, et al
Take Home Message Psoriasis is not just a skin disease but a systemic inflammatory condition that significantly increases cardiovascular risk
Akil H, Burgess J, Nevitt S, Harding SP, Alam U, Burgess P