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These alternate metabolic routes lead to accumulation of toxic intermediates and advanced glycation end products, promoting inflammation, cellular dysfunction, apoptosis, and fibrosis within kidney tissues [24,25]

[PubMed] Voronkov DN, Stavrovskaya AV, Stelmashook EV, Genrikhs EE, Isaev NK (2019) Neurodegenerative changes in rat brain in streptozotocin model of Alzheimers disease

When fluids are low, the urine can look darker yellow or orange

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NTS-enriched micropunches were taken at the level of the AP (from bregma, AP 13.0 to 14.8 mm) and RNA was extracted according to manufacturers instructions (TRI Reagent