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Semaglutide is a receptor agonist, meaning it mimics the action of natural hormones like GLP-1 by activating their receptors, which helps regulate appetite and blood sugar levels
Off-Label Prescriptions for Pediatric Patients Lawsuits also focus on off-label prescriptions for pediatric patients, where children and teens were prescribed GLP-1 drugs such as Ozempic and Wegovy without FDA approval for this age group
Figure S16
Another DAMP, IL-33, activates HSCs either directly or through innate lymphoid cells (ILCs)
PMID: 2237408
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![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/400539064/figure/fig1/AS:11431281970083405@1772162745620/Effect-of-GLP-1RA-Therapy-on-Kidney-Damage-and-Progression-in-Diabetic-Kidney-Disease_Q320.jpg)
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