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Subsequent investigations identified NNMT as a potential target for studying obesity, energy expenditure, and metabolic disorders

Anyone with Wilson's disease, other copper-metabolism disorders, or during pregnancy should consult a healthcare professional before use

In these cases, injections are a more effective way of delivering the vitamin directly into the bloodstream, bypassing the digestive system

The beneficial effects shown on animals can differ or even be negative when the substance is given to humankind

These effects are thought to be mediated by the neurotrophic actions of IGF-1, which crosses the blood-brain barrier and activates neuronal survival and synaptic plasticity pathways