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M.CryanJ
High-polyphenol EVOO is a nutritional tool that may support metabolic health through multiple mechanisms, including modest support of natural GLP-1 secretion
"Orlistat + L-carnitine in obese diabetic patients." Endocr J 2010;57:777-86
The results: 35% reduction in body mass 30% decrease in adipocyte size 40% decrease in adipocyte volume No change in food intake (meaning the weight loss was purely metabolic) Cholesterol levels normalized to those of lean mice This is fundamentally different from appetite suppressants like GLP-1 agonists
Track mean plasma IGF1 to gauge response and safety since IGF1 elevation links to both benefits and theoretical cancer risks
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