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With caloric intake reduced 30-50% and the body adapting to powerful medications, recovery capacity decreases
Efficacy and safety of once-weekly semaglutide 20 mg versus 10 mg in patients with type 2 diabetes (SUSTAIN FORTE): a double-blind, randomised, Phase 3B trial
Common sense, yesbut critical for long-term success
Research suggests that these medications can help reduce abdominal obesity, improve insulin sensitivity, lower blood glucose levels, and decrease inflammatory signalingall of which are key drivers of cardiovascular disease in postmenopausal women
Its main effects include: Increasing lipolysis (fat breakdown) Reducing lipogenesis (fat storage) Improving fat metabolism signaling Doing so without affecting muscle, bone, or glucose regulation Importantly: It does not stimulate growth hormone release It does not rely on pituitary feedback loops It does not act on central appetite pathways This is why it has such a clean safety profile
