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Pre-existing osteoarthritis, increased physical activity, dehydration, and weight-loss-triggered gout flares may also contribute
Schedule regular appointments to assess glycemic control (through A1C testing), weight changes, and tolerability
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Gastrointestinal Side Effects Both Zepbound and Metformin commonly cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and constipation, especially when starting treatment or increasing doses
GLP-1 Origin Initially, it was hypothesized that GLP-1 was derived from proglucagon, a 158-amino-acid precursor, specifically from the N-terminal region of the major proglucagon fragment (MPGF)
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