This plumps the skin from within, reducing the visibility of fine lines caused by dryness
GSH is synthesized via two ATP-dependent steps: first, -glutamyl cysteine is formed from glutamate and cysteine by -glutamyl cysteine ligase (GCL), the rate-limiting enzyme [9]
Upregulated: collagen synthesis genes (COL1A1, COL3A1), antioxidant genes (SOD1, SOD3), DNA repair genes (GADD45A) Downregulated: inflammatory cytokines (IL-6, TNF-), metalloproteinases (MMP-2, MMP-9), pro-fibrotic mediators Net effect: shift from tissue destruction and inflammation toward repair and remodeling This breadth of gene modulation is unusual for a single tripeptide and has generated significant research interest in fields ranging from dermatology to neuroscience
60,61 Importantly, those who undergo radioiodine treatment should reduce exposure to other people for a period after taking the radioiodine, especially pregnant women
Further reading [edit] Enzyme Systems That Metabolise Drugs and Other Xenobiotics