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The mechanism of action is multifactorial, directly or indirectly upregulating cell growth, proliferation, survival, angiogenesis, and anti-inflammation pathways

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Maquart, Pickart, and colleagues established this in fibroblast culture in 1988 ( FEBS Letters ) and confirmed it in vivo in rat wound models in 1993 ( Journal of Clinical Investigation ) 5 6

BPC-157 vs LL-37 BPC-157 and LL-37 are both studied for wound healing but through distinct mechanisms: BPC-157 promotes tissue repair through angiogenesis, fibroblast activation, and nitric oxide modulation

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