Anti-Aging Benefits: The powerful antioxidant properties of Glutathione helps to protect your skin from free radical damage, reducing the appearance of fine lines, wrinkles, and other signs of aging
Theoretical concerns include excessive sirtuin activation potentially accelerating certain cancers (NAD+ fuels rapidly dividing cells) and methylation pathway depletion (NAD+ synthesis via the salvage pathway consumes methyl groups)
In other words, stopping insulin might cause a spike in a patients A1C levels, and a person who ceases use of beta blockers for hypertension could see elevated blood pressure
Hepatology 78 , 389396 (2023)
Medicare currently covers GLP-1s for diabetes, sleep apnea, cardiovascular risk reduction, and MASH