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It has been described that FGF-2 can promote angiogenesis acting together with VEGF, by inducing the secretion of MMPs, plasminogen activator and collagenase responsible for the degradation and organization of the extracellular matrix [134]
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Avoid strong exfoliating acids (like glycolic, lactic, or salicylic acid), low-pH Vitamin C (ascorbic acid), and retinoids
The review calls for simultaneous registration of physiological effects and binding site detection as the methodology most likely to resolve DSIPs mechanism
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