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Understanding why the evidence for DSIP is weak, and being able to say so plainly, is itself a clinical skill
But which option should you actually choose
The 20-day standard protocol This represents the most commonly cited approach in published research and clinical practice
However, Put has a more robust sleep-promoting effect in the fruit fly model than either L-ornithine or Spd, and blocking the conversion of Put into Spd/Spm also increases sleep (Xu et al., 2016
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