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That level of investment signals genuine scientific confidence, not casual curiosity
Hasan AA, Hocher B
The 56-week COR-I trial studied the use of Contrave in patients with a BMI of 27 or higher and found that participants taking a combination of naltrexone and bupropion lost an average of 4.8% more weight than those given a placebo
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Of note, a small number of cases of acute pancreatitis associated with GLP-1RA use have been reported in clinical trials: 38 cases in 17,775 patient-years of exposure compared with 9 events in 5863 patient-years of exposure with the comparator treatment
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