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An uncontrolled study of a self-limiting condition cannot establish efficacy, and this work was never replicated under controlled conditions which, four decades on, is itself the most informative fact about it

The risk with topical use is relatively low since systemic absorption is limited

Topical glutathione such as creams and serums

For example, researchers found that once antibodies bound to the drug, the drug stayed in the bodythough neutralizedfor a long time

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